Virtual Reality (VR) is an emerging technology and has enormous potential for improving/complementing psychotherapy. It provides simulated environments that can be hard to present in in-vivo trials, which can help persons with difficulties in imagining situations they feel anxious or relaxed in. We examined the effectiveness of VR on anxieties among participants, such as dental fear, public speech anxiety, test anxiety, and heterosocial anxiety. Except the case of dental fear where we provided relaxing environment (a ‘beach’, in this case), the feared scenes were utilized to implement behavioral exposure therapy with which ‘extinction’ of anxiety reactions are expected. The analyses of data yielded promising results: the participants in VR groups showed statistically significant anxiety reduction in comparison to control groups even if the duration of VR program was relatively short. In addition, the dropout rates in VR groups were lower than in traditional behavioral exposure therapy. The participants, however, reported a few things to be complemented and the researchers who manipulated the system also pointed out a few concerns. For example, the heaviness of head-mounted display made it hard for female participants to move freely and their diversity of ideal types of men (in the case of heterosocial anxiety) could not be reflected in VR programs. Our series of trials revealed that VR applications leave much to be desired. On this poster, several captured shots from the VR scenes utilized in our trials will be also presented and challenges to overcome for effective applications will be discussed.